Hi DeeDee - I can completely empathise with your situation. I will try to answer your questions as simply as possible. The symptoms of acute retroviral syndrome are caused by the bodies reaction to a rapid increase in the numbers of the virus in the blood stream. Some of the symptoms do not require antibodies to appear. However, this expansion of the virus very quickly - 24hrs to 7 days - leads to the production of antibodies that can be detected by the BioSURE HIV self test. At 41 days a negative BioSURE HIV Self Test would be very encouraging but could not be relied on. Our best estimate would be that a negative result would be correct just over 90% of the time. From what you have described your best outcome will come from the 4th generation test that you are waiting results for. By all means take the BioSURE HIV Self Test. If it is positive the result would be accurate. If negative as I said it will be about 90% reliable. All the test results you have received are very encouraging. The results of your generation test will be definitive. I am sorry that I can't provide more certainty at this time, but you have already taken the best actions. Please let me know how everything works out. Kindest regards Gary Carpenter BioSure (UK) Limited